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Alison Bates, Ph.D.

Faculty Default Image
Operations Lab Manager
Department of Biology
Oldenburg Hall, Room 258B

Biography

I am a molecular biology research scientist serving as the Laboratory Operations Manager for the Biology and Chemistry departments in the College of Arts and Sciences. I also conduct my own research on improving CRISPR gene editing methods in Streptomyces bacteria.

I hold a double major Bachelor's degree in Vocal Music Performance and Biological Sciences from DePauw University, as well as a Master of Music degree in Vocal Music Performance from the Jacobs School of Music at Indiana University. I first pursued a career as a professional opera singer, performing with Chautauqua Opera, Glimmerglass Opera, Minnesota Opera, and Palm Beach Opera, as well as numerous other symphony orchestras and performing ensembles.

I then attended the Indiana University School of Medicine, obtaining a Master of Science degree in Cellular and Integrative Physiology and a Ph.D. in Biochemistry and Molecular Biology, conducting research in telomere dysfunction in ovarian cancer, Wnt signaling in pancreatic cancer, and 3-dimensional DNA organization in human cells, all with an emphasis on CRISPR genetic engineering.

I have since worked in multiple biotech industry roles, developing CRISPR gene editing platforms in Streptomyces bacteria and developing high-throughput transfection-grade plasmid purification systems. I am passionate about CRISPR gene editing and genomics research, and I enjoy having the opportunity to share my love of DNA with students as a research mentor in addition to my lab management role.

 

 

Selected Publications:

  • Chen, Q., A. M. Bates, J. N. Hanquier, E. Simpson, D. B. Rusch, R. Podicheti, Y. Liu, R. C. Wek, E. M. Cornett, and M. M. Georgiadis. Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing. J Biol Chem 298, 101894 (2022).
  • Huda, N., Y. Xu, A. M. Bates, D. A. Rankin, N. Kannan, and D. Gilley. Onset of Telomere Dysfunction and Fusions in Human Ovarian Carcinoma. Cells 8, (2019).
  • Hoshika, S., N. A. Leal, M. J. Kim, M. S. Kim, N. B. Karalkar, H. J. Kim, A. M. Bates, N. E. Watkins, Jr., H. A. SantaLucia, A. J. Meyer, S. DasGupta, J. A. Piccirilli, A. D. Ellington, J. SantaLucia, Jr., M. M. Georgiadis, and S. A. Benner. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science 363, 884–887 (2019).
  • Tu, L., N. Huda, B. R. Grimes, R. B. Slee, A. M. Bates, L. Cheng, and D. Gilley. Widespread telomere instability in prostatic lesions. Mol Carcinog 55, 842–852 (2016).
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