Samina Akbar, Ph.D.

Investigator Page

Background

Ph.D. from University of California Davis, 1997 in Microbiology and Molecular Biology.  Postdoctoral research with Dr. Cathy Lee, Harvard Medical School, 1999-2002.  Post graduate research at University of British Columbia Center for Disease Control, Vancouver Canada, 2002-2007.

Research Interests:

Bacterial Pathogenesis, Multiple Drug Resistance in bacteria.

Research Projects:
  • Molecular analysis of the large multidrug resistant CMY2 plasmids present in Salmonella species isolated from both humans and animal gut.

  • Role of the large plasmids in the virulence of Salmonella species.

  • Determining the role of integrons and genomic islands in the spread of antibiotic resistance in Salmonella species.

Representative Publications

Kempf, A.J., Hulsebus, H.J., and S. Akbar. Multiple Plasmids contribute to Antibiotic resistance and Macrophage survival in CMY2-bearing Salmonella enterica. Foodborne Pathogens and Disease. 2016. 13(7): 398-404

H.J. Hulsebus and S. Akbar. Preliminary Investigation of Integron-associated Multidrug Resistance in Salmonella enterica isolated from Human and Animal Sources. Manuscript in Preparation.

Hamilton, R.D., H.J. Hulsebus, S. Akbar, and J.T. Gray. Increased Resistance to Multiple Antimicrobials and Altered Resistance Gene Expression in CMY-2-Positive Salmonella Following a Simulated Patient Treatment with Ceftriaxone. 2012. Appl. Env. Microbiol. 78:8062-8066.

Schechter, L. M., S. Jain, S. Akbar, and C. A. Lee. 2003. The small nucleoid-binding proteins H-NS, HU, and Fis affect hilA expression in Salmonella enterica serovar Typhimurium. Infect. Immun. 71:5432-5.

Akbar, S., C. P. Lostroh, L. M. Schechter, and C. A. Lee. 2003. HilD has a direct role in the activation of invasion gene expression in Salmonella typhimurium. Mol. Microbiol. 47:715-28.

 

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