David Gardner, Ph.D.
Professor of Biochemistry

(317) 955-6283
Evans Center, Room 312C

Clinical/Research Interests

  • EGF Receptor Signaling in Squamous Cell Carcinoma.
  • Function of Homeobox gene Hoxc-8 during vertebrate development.
  • Effects of ethanol on limb development in a mouse model of fetal alcohol syndrome.
  • Integration of biomedical science topics into 3rd and 4th year medical school curriculum: The Totally Basic Science Podcast
  • Development of critical thinking skills during medical school.  

Representative Publications

Chrisman K, Kenney R, Comin J, Thal T, Suchocki L, Yueh YG, Gardner DPGestational ethanol exposure disrupts the expression of FGF8 and Sonic hedgehog during limb patterning. Birth Defects Res A Clin Mol Teratol. 2004 Apr;70(4):163-71.

Yueh YG, Gardner DP, Kappen C. Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9956-61.

Gardner DP, Byrne GW, Ruddle FH, Kappen C. Spatial and temporal regulation of a lacZ reporter transgene in a binary transgenic mouse system. Transgenic Res. 1996 Jan;5(1):37-48.

Rundle CH, Macias MP, Yueh YG, Gardner DP, Kappen C. Transactivation of Hox gene expression in a VP16-dependent binary transgenic mouse system. Biochim Biophys Acta. 1998 Jun 16;1398(2):164-78.

Gardner DP, Shimizu N. Loss of cytotoxic effect of epidermal growth factor (EGF) on EGF receptor overexpressing cells is associated with attenuation of EGF receptor tyrosine kinase activity. J Cell Physiol. 1994 Feb;158(2):245-55.

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