Bhupal P. Bhetwal, M.Sc., Ph.D. is a teaching fellow of Biochemistry and Molecular Cell Biology at MU-COM. Dr. Bhupal P. Bhetwal earned his Masters of Science in Human Physiology from B. P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal. After teaching Medical Physiology at BPKIHS for four years, he came to the United States for pursuing Ph.D. He earned his Ph.D. in Cellular & Molecular Pharmacology & Physiology from the University of Nevada School of Medicine (UNSOM), Reno (2007-12) in Dr. Brian A. Perrino's laboratory. After his Ph.D., Dr. Bhetwal pursued his first post-doctoral research training with Dr. Wei Yan and Dr. Kenton M. Sanders in Reno (2012-14) and second post-doctoral research training with Dr. Susan J. Gunst at the Indiana University School of Medicine, Indianapolis (2014-16).
Dr. Bhupal Bhetwal's research interests are in smooth muscle contractility and intracellular signaling. Smooth muscles line the inner walls of many hollow organs such as gastrointestinal tract, reproductive tract, airways, uterus, blood vessels, urinary bladder etc. Hence signaling pathways that regulate smooth muscle tone in these organs are of clinical interests. Dr. Bhetwal's master's degree dissertation focused on cardiovascular fitness changes due to physical activity and high altitude adaptation and his doctoral dissertation focused on studying role of Ca2+ sensitization pathways in regulating gastrointestinal smooth muscle contractility in health and chronic diabetes. At MU-COM, Dr. Bhetwal is setting up to extend his research in studying intracellular signaling pathways in various tissues/organs between healthy and obese-diabetic animals and correlate signaling changes with functional changes in tissues/organs. He collaborates with the faculties at the Indiana University School of Medicine, Indianapolis and with biomedical science faculties at the MU-COM for his ongoing research projects.
Dr. Bhetwal enjoys teaching students with clinical applications of the Biochemical/Physiological concepts. He is a member of the American Physiological Society, American Neurogastroenterology and Motility Society, and American Society for Pharmacology and Experimental Therapeutics. Learn more about Dr. Bhetwal in this Q&A.